Neural organoids are self-assembled three-dimensional aggregates generated from iPSCs or other stem cells with cell types and cytoarchitectures that resemble the (embryonic) human brain. Neural organoids have emerged as novel model systems that can be used to study human brain development and disease. In our facility we use neural organoids for modelling different neurological and psychiatric diseases. Protocols for generating different types of organoids are in place (e.g. cerebral, cortical) as well as methods to isolate specific cell types from organoids, e.g. microglia, astrocytes.
If you have questions or would like to discuss a potential project, please use the application form.